Breast cancer risk is more affected by total body fat than abdominal fat
Body fat is a known risk factor for postmenopausal breast cancer but whether there is an increased risk from fat specifically accumulated around the stomach is unclear. In recent years, belly fat has been reported to raise the risk of several conditions including cardiovascular disease, type-2 diabetes and colorectal cancer. Increased levels of several blood markers, including sex hormones, testosterone and oestrogen, the "fullness hormone," leptin, and inflammatory f actors, are associated with breast cancer risk. Some research has suggested that these markers are mainly produced in fat localised to the belly while other work has shown that weight loss is associated with changes in blood levels of breast cancer markers. Taken together these findings seem to suggest that body fat could have an important effect on breast cancer markers. In this study, carried out by researchers at the University Medical Center Utrecht in the Netherlands, 243 overweight, postmenopausal wo...